Discontinue treatment in cases of HTN, tachycardia, palpitations or cardiac arrhythmias, nausea, headache. History of MI, DM, bladder neck obstruction or +ve anamnesis of bronchospasm. Stenosing peptic ulcer, pyloroduodenal & vesical cervix obstruction. Treatment w/ digitalis, sympathomimetics including decongestants, anorexogenics or amphetamine-type psychostimulants, antihypersensitive agents, TCAs & other antihistamines. Patients w/ migraine under ergot alkaloid vasoconstrictor treatment; peri-op acute HTN. Discontinue 24 hr before anesth. Discontinue use 48 hr before skin tests. May be +ve in doping test. Pregnancy & lactation.