Slow bolus inj or infusion Induction of anesth Usual dose:
Adult 2-2.5 mg/kg.
Childn >8 yr 2.5 mg/kg.
<8 yr ≥2.5 mg/kg. Maintenance dose:
Adult 4-12 mg/kg/hr as continuous infusion or repeat bolus inj dose of 25-50 mg.
Childn 9-15 mg/kg/hr.
Elderly, debilitated or ASA III/IV patients Induction of general anesth 20 mg/10 sec (1-1.5 mg/kg).
Maintenance of general anesth 50-100 mcg/kg/min (3-6 mg/kg/day).