Ardeparin: Indication, Dosage, Side Effect, Precaution

This information is not country-specific. Please refer to the Indonesia prescribing information.

Generic Medicine Info

Indications and Dosage

Subcutaneous
Prophylaxis of deep vein thrombosis

Adult: Initially 50 iu/kg following surgery. Subsequently, 50 iu/kg bid for 14 days after surgery or until ambulatory.

Contraindications

Hypersensitivity, thrombocytopaenia, active major bleeding, active peptic ulcer.

Special Precautions

Renal or hepatic impairment, history of GI ulceration, uncontrolled hypertension, spinal or epidural anaesthesia. Pregnancy, lactation; elderly. Periodic blood counts, including platelet count and stool occult blood test recommended.

Adverse Reactions

Thrombocytopaenia, mild bleeding, Inj site irritation, pain and ecchymoses, hypersensitivity and erythema.
Potentially Fatal: Haemorrhagic complications.

Drug Interactions

Potentially Fatal: Risk of haemorrhage increased with oral anticoagulants, platelet aggregation inhibitors, NSAIDs including aspirin.

Action

Description:
Mechanism of Action: Ardeparin Na is a LMWH with anticoagulant activity. It has been used for the prevention of post-op venous thromboembolism.
Pharmacokinetics:
Excretion: Elimination half-life: 3.5 hr.

MIMS Class

Anticoagulants, Antiplatelets & Fibrinolytics (Thrombolytics)

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