Beraprost: Indication, Dosage, Side Effect, Precaution

This information is not country-specific. Please refer to the Indonesia prescribing information.

Generic Medicine Info

Indications and Dosage

Oral
Peripheral vascular disease

Adult: 120 mcg/day in 3 divided doses.

Oral
Primary pulmonary hypertension

Adult: Initially, 60 mcg daily, given in 3 divided doses, may increase to 180 mcg daily, given in 3-4 divided doses if necessary.

Administration

Should be taken with food.

Contraindications

Patients with haemorrhage. Pregnancy.

Special Precautions

Patients on anticoagulants, antiplatelet or fibrinolytic agents. Menstruating women, patients with bleeding tendency or diathesis. May enhance bleeding tendency.

Adverse Reactions

Headache, hot flushes, GI upset, bleeding tendency, dizziness. Increased liver enzymes, triglycerides and bilirubin.

Drug Interactions

Anticoagulants, antiplatelet, fibrinolytic agents or any product that intensifies bleeding tendency. Prostaglandin I₂ preparations.

Action

Description:
Mechanism of Action: Beraprost is a synthetic analog of epoprostenol (a prostaglandin) which causes vasodilatation and prevents platelet aggregation.

MIMS Class

Anticoagulants, Antiplatelets & Fibrinolytics (Thrombolytics) / Peripheral Vasodilators & Cerebral Activators

Disclaimer: This information is independently developed by MIMS based on Beraprost from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2024 MIMS. All rights reserved. Powered by MIMS.com