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Indications and Dosage
Oral
Bacterial diarrhoea Adult: 1-2 tab bid.
Child: 5-15 years 1 tablet twice a day, 15 years Same as adult, or as directed by a physician. |
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Contraindications
Pregnancy, lactation. Infants & young children.
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Adverse Reactions
High doses of berberine >500mg (corresponding to 8-100 g of dried goldenseal root) can cause stomach upset, nausea,
vomiting, nervousness, depression, dyspnoea, bradycardia, cardiac damage, hypotension, seizures, paralysis, spasms & death.
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Action
Description:
Mechanism of Action: Decreases anticoagulant effect of heparin in laboratory tests of heparinated animal & human blood. Act as cardiac stimulant in low doses, increases coronary perfusion & inhibits cardiac activity at high doses in animals. Antipyretic activity, anthelmintic, antihistaminic, antimicrobial, antimuscarinic, antitumorigenic & hypotensive effects have been documented in animals & laboratory models. Duration: 8 hr. Pharmacokinetics: Absorption: Absorbs slowly orally. Peak plasma conc is achieved in 4 hr. Excretion: Excretes in the urine. |
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MIMS Class
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