Gastrointestinal motility disorders, Nausea and vomiting
Adult: 20-60 mg daily in divided doses.
Parenteral
Gastrointestinal motility disorders, Nausea and vomiting
Adult: IV/IM: 20 mg daily.
Indications and Dosage
Oral
Gastrointestinal motility disorders, Nausea and vomiting Adult: 20-60 mg daily in divided doses. Parenteral Gastrointestinal motility disorders, Nausea and vomiting Adult: IV/IM: 20 mg daily.
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Contraindications
GI haemorrhage, obstruction, perforation or immediately after surgery. Patients with pheochromocytoma.
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Special Precautions
Children, young patients, elderly; renal impairment, epilepsy, Parkinson's disease; history of depression. May impair ability to drive or operate machinery.
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Adverse Reactions
Extrapyramidal symptoms; restlessness, drowsiness, diarrhoea; hypotension, hypertension, dizziness, headache, depression; galactorrhoea.
Potentially Fatal: Neuroleptic malignant syndrome. |
Drug Interactions
Other centrally active drugs and those with extrapyramidal effects. Increased toxicity with lithium. Antagonism of GI effects with antimuscarinics and opioid analgesics. May affect absorption of other drugs.
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Lab Interference
Transient increase in plasma-aldosterone concentration.
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Action
Description:
Mechanism of Action: Bromopride is a substituted benzamide with prokinetic and antiemetic properties. |