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Indications and Dosage
Oral
Cerebrovascular and peripheral vascular disease Adult: 3-12 mg 3-4 times/day, up to 90 mg/day.
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Contraindications
MI, hyperthyroidism, paroxysmal tachycardia, severe angina.
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Special Precautions
Peptic ulcers, tachyarrhythmias, uncompensated CCF. Pregnancy and lactation.
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Adverse Reactions
Trembling, nervousness, weakness, dizziness, palpitations, nausea, vomiting, anaemia.
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Action
Description:
Mechanism of Action: Buphenine is a sympathomimetic that produces peripheral vasodilatation via stimulation of beta-adrenoceptors. It also acts directly on the arteries and arterioles of the skeletal muscles. It also suppresses uterine contractility thereby preventing premature labour. |
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