Dietary supplement
Adult: 300-600 mg (as elemental Ca) daily in divided doses.
Indications and Dosage
Oral
Dietary supplement Adult: 300-600 mg (as elemental Ca) daily in divided doses.
|
Administration
Should be taken with food.
|
Contraindications
Conditions associated with hypercalcaemia and hypercalciuria.
|
Special Precautions
Patient with sarcoidosis, history of nephrolithiasis. Renal impairment. Pregnancy.
|
Adverse Reactions
Gastrointestinal disorders: Constipation, bloating, gas.
|
IM/Parenteral: C
|
Drug Interactions
May increase the risk of hypercalcaemia with thiazide diuretics. May enhance the effects of digitalis. Increased absorption with vitamin D. Reduced absorption with corticosteroids. May reduce absorption of bisphosphonates, fluoride, fluoroquinolones and tetracyclines.
|
Action
Description:
Mechanism of Action: Ca lactate is used to treat or prevent negative serum Ca balance. It also helps prevent or reduce the rate of bone loss, moderate nerve and muscle performance, and allow normal cardiac function. Pharmacokinetics: Absorption: Absorbed mainly from the small intestine via active transport and passive diffusion. Distribution: Crosses the placenta and enters the breast milk. Plasma protein binding: 45%. Excretion: Primarily via faeces as unabsorbed calcium. |
Chemical Structure
|
Storage
Store below 25°C.
|
MIMS Class
|
ATC Classification
A12AA05 - calcium lactate ; Belongs to the class of calcium-containing preparations. Used as dietary supplements.
|
References
Anon. Calcium lactate. Lexicomp Online. Hudson, Ohio. Wolters Kluwer Clinical Drug Information, Inc. https://online.lexi.com. Accessed 08/05/2020. Anon. Calcium Salts. AHFS Clinical Drug Information [online]. Bethesda, MD. American Society of Health-System Pharmacists, Inc. https://www.ahfscdi.com. Accessed 08/05/2020. Buckingham R (ed). Calcium. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 08/05/2020. Calcium Lactate Tablets BP 300 mg (Accord-UK Ltd). MHRA. https://products.mhra.gov.uk/. Accessed 08/05/2020. Calcium Lactate Tablets BP 300 mg (Dalkeith Laboratories Ltd). MHRA. https://products.mhra.gov.uk/. Accessed 24/06/2020. Joint Formulary Committee. Calcium Lactate. British National Formulary [online]. London. BMJ Group and Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 08/05/2020.
|