Adult Initial dose: 4-80 mg daily. Maintenance dose: 4-8 mg daily, may be increased up to 16 mg daily. Childn Initial dose: 0.8-1.1 mg/kg. Maintenance dose: 2-4 mg daily, may be increased up to 8 mg daily. Adjuvant to mineralocorticoid therapy in Addison's disease Substitution dose: 4-8 mg in stressful situation, up to 16 mg daily.
Patients w/ severe HTN & cardiac insufficiency. May produce subcapsular cataracts, glaucoma & enhance the establishment of fungi or virus infections. Carry out ophth control every 3 mth in long-term treatment. Re-examine blood & urine sugar values in diabetic patients. May mask signs of infection. Not to be discontinued abruptly but gradually. Increase dosage in patients w/ stressful situation. Patients should not receive smallpox or other high-dose vaccines. Monitor carefully patients w/ TB-latent or tuberculine reactivity. May potentiate glucocorticoid effects in patients w/ hypothyroid or hepatic cirrhosis. Not recommended for pregnant women & nursing mothers. May inhibit growth & development w/ prolonged use in childn.
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