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Indications and Dosage
Parenteral
Intestinal colic, Biliary colic, Renal colic, Dysmenorrhoea Adult: 1mL (25 mg) by IM or IV Inj up to a max of tid.
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Contraindications
Narrow-angle glaucoma, prostatic hypertrophy, mechanical stenoses.
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Special Precautions
Camylofin Inj must be administered with care in thyrotoxicosis, obstructive airway disease, during cardiac surgery, elderly or those with fever.
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Adverse Reactions
Injection may cause skin rashes, other allergic reactions and infrequently atropine-like side effects.
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Drug Interactions
Camylofin Inj should be co-administered with caution in patients taking amantadine, quinidine and tricyclic antidepressants.
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Action
Description:
Mechanism of Action: Camylofin is a smooth muscle relaxant with both anticholinergic action as well as direct smooth muscle action. Anticholinergic action is produced by inhibiting the binding of acetylcholine to muscarinic receptors, but the action is less pronounced. Direct smooth muscle relaxation is achieved by inhibiting phosphodiesterase type IV, which leads to increased cyclic AMP and eventually reduced cytosolic calcium. Thus camylofin has a comprehensive action to relieve smooth muscle spasm. |
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MIMS Class
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