Resp tract infections especially pneumonia, ENT infections; UTI; genital infections including gonorrhoea; bone, joint, soft tissue, skin & wound infections; sepsis; endocarditis; meningitis; abdominal infections ie, peritonitis, gallbladder infections, GI infections; pre-op prophylaxis; infection in immunocompromised patients.
Dosage/Direction for Use
Adult & childn >12 yr Usual dose: 1 g 2 times daily (12 hrly), may be increased to max 12 g in severe cases. Gonorrhoea 1 g IM as a single dose. Uncomplicated infection 1 g IM/IV 12 hrly. Moderate to severe infection 1-2 g IM/IV 8 hrly. High-level infection 2 g IV 6-8 hrly.
Contraindications
Hypersensitivity to cephalosporins.
Special Precautions
Cross-allergic reaction may occur in patients hypersensitive to penicillin or other β-lactam antibiotics. Monitor kidney function in patients receiving aminoglycosides. Monitor haematologic effects in long-term use (>10 days). Prolonged use may cause resistance. Pregnancy, lactation.
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