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Indications and Dosage
Topical/Cutaneous
Antiseptic agent Adult: As soln containing cetrimide 0.15 mg/mL and chlorhexidine 1.5 mg/mL: To be used as directed by the product.
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Contraindications
Not to be used in the eye, ear, mucous membrane or body cavities.
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Special Precautions
Prolonged and repeated use may increase risk of hypersensitivity reactions. Blood, soap, cotton or other organic matter may decrease antibacterial efficacy.
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Adverse Reactions
Repeated application may lead to skin irritation.
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Overdosage
Accidental ingestion may lead to nausea and vomiting, dyspnoea and cyanosis due to paralysis of the respiratory muscles, may also cause asphyxia, depression of the CNS with convulsions, hypertension and coma may occur. Treatment is supportive and includes gastric lavage with water and charcoal.
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Action
Description:
Mechanism of Action: Cetrimide is a quaternary ammonium antiseptic; it has bactericidal activity against both gram-positive and gram-negative organisms. Chlorhexidine is an antimicrobial agent; it is active against a wide range of gram-negative and gram-positive vegetative bacteria, yeasts, dermatophyte fungi and lipophilic viruses. Pharmacokinetics: Absorption: Chlorhexidine: Poorly absorbed through the skin. |
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Storage
Store at room temperature.
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MIMS Class
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