Cetrimide: Indication, Dosage, Side Effect, Precaution

Generic Medicine Info Patient Medicine Information

This information is not country-specific. Please refer to the Indonesia prescribing information.

Generic Medicine Info

Indications and Dosage

Topical/Cutaneous
Antiseptic

Adult: As cetrimide 0.5% or 1% cream, or 1% or 2% lotion: Apply liberally to the affected area(s) as required. As cetrimide 0.5% spray solution: Spray to the affected area(s) 2-3 times daily.

Incompatibility

Incompatible with anionic surfactants, soaps, bentonite, iodine, phenylmercuric nitrate, alkali hydroxides.

Contraindications

Hypersensitivity.

Adverse Reactions

Significant: Hypersensitivity (prolonged and repeated use).
Skin and subcutaneous tissue disorders: Localised contact dermatitis; skin irritation, sensitisation, or dryness.

Patient Counseling Information

Avoid application on weeping or badly inflamed skin.

Action

Description:
Mechanism of Action: Cetrimide is a quaternary ammonium antiseptic with bactericidal action against gram positive and some gram negative (at higher concentrations) organisms, but ineffective against bacterial spore. It has variable antifungal activity and effective against some viruses.

Chemical Structure

Storage

Store below 30°C. Protect from light, heat and moisture.

MIMS Class

Skin Antiseptics & Disinfectants

ATC Classification

D08AJ04 - cetrimide ; Belongs to the class of quaternary ammonium compound antiseptics. Used in the treatment of dermatological diseases.
D11AC01 - cetrimide ; Belongs to the class of medicated shampoos.

References

Anon. Cetrimide. Lexicomp Online. Hudson, Ohio. Wolters Kluwer Clinical Drug Information, Inc. https://online.lexi.com. Accessed 05/05/2021.

Buckingham R (ed). Cetrimide. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 05/05/2021.

Cetavlex Cream (Derma UK Ltd). MHRA. https://products.mhra.gov.uk. Accessed 05/05/2021.

First Aid Antiseptic Spray or Boots Antiseptic Wound Wash (The Boots Company PLC). MHRA. https://products.mhra.gov.uk. Accessed 05/05/2021.

Vesagex Antiseptic Cream (Strides Pharma UK Ltd). MHRA. https://products.mhra.gov.uk. Accessed 05/05/2021.

Xortrim 1 1% w/v Lotion (Xorix Sdn Bhd). National Pharmaceutical Regulatory Agency - Ministry of Health Malaysia. https://www.npra.gov.my. Accessed 05/05/2021.

Xortrim 1,2; 1%, 2% w/v Lotion (Xorix Sdn. Bhd.). MIMS Malaysia. http://www.mims.com/malaysia. Accessed 20/05/2021.

Disclaimer: This information is independently developed by MIMS based on Cetrimide from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2024 MIMS. All rights reserved. Powered by MIMS.com