Cetylpyridinium chloride: Indication, Dosage, Side Effect, Precaution

Generic Medicine Info Patient Medicine Information

This information is not country-specific. Please refer to the Indonesia prescribing information.

Generic Medicine Info

Indications and Dosage

Mouth/Throat
Sore throat

Adult: As 0.025% liquid: Gargle with 15 mL of undiluted liquid bid or tid. Do not swallow.
Child: >6 years Same as adult dose.

Mouth/Throat
Antiseptic, Mouth infections, Oral hygiene

Adult: As mouthwash: Rinse mouth with 15 mL or 20 mL for 30 seconds bid or tid. Do not swallow.
Child: ≥6 years Same as adult dose.

Topical/Cutaneous
Minor, superficial skin wounds, Superficial burns

Adult: As 0.025% liquid: Apply undiluted liquid onto the affected area.
Child: Same as adult dose.

Incompatibility

Incompatible with anionic surfactants (e.g. soaps).

Special Precautions

Children.

Adverse Reactions

Gastrointestinal disorders: Dental or tongue discolouration, mouth irritation.
Immune system disorders: Hypersensitivity reactions.

Patient Counseling Information

Do not use over extensive areas of the body or use for prolonged periods. Avoid contact with eyes.

Overdosage

Symptoms: Accidental ingestion of large quantities may result in pain, nausea, vomiting, diarrhoea, slurred speech, euphoria, muscle incoordination, impaired consciousness, coma, and hypoglycaemia in children. Management: Supportive treatment. Perform gastric aspiration and lavage. Administer oral or IV glucose for hypoglycaemia in children.

Action

Description:
Mechanism of Action: Cetylpyridinium chloride, a quaternary cationic antiseptic with activity against both gram-positive and gram-negative organisms.

Chemical Structure

Storage

Store below 30°C. Protect from light.

MIMS Class

Preparations for Oral Ulceration & Inflammation / Skin Antiseptics & Disinfectants

References

Advanced Guard Rinse (H-E-B). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/. Accessed 06/08/2020.

Alcohol Free Antiseptic Mouthwash (Rite Aid). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/. Accessed 06/08/2020.

Anon. Cetylpyridinium. Lexicomp Online. Hudson, Ohio. Wolters Kluwer Clinical Drug Information, Inc. https://online.lexi.com. Accessed 06/08/2020.

Buckingham R (ed). Cetylpyridinium Chloride. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 06/08/2020.

First Aid Antiseptic Liquid or Antiseptic Liquid (The Boots Company PLC). MHRA. https://products.mhra.gov.uk/. Accessed 06/08/2020.

Therabreath Healthy Gums Oral Rinse (Dr. Harold Katz, LLC). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/. Accessed 06/08/2020.

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