Coyarin Dosage & Drug Information

Concise Prescribing Info Bahasa Concise Prescribing Info

Concise Prescribing Info

Contents

Amoxicillin trihydrate 575 mg (equiv to amoxicillin 500 mg), clavulanate K 309 mg (equiv to clavulanic acid 125 mg)

Indications/Uses

Upper & lower resp tract, GUT, skin & soft tissue, bone & joint, tooth infections & other infections (ie, abortion sepsis, puerperal sepsis, intra-abdominal sepsis).

Dosage/Direction for Use

Adult & childn >12 yr Mild to moderate infections 1 caplet 312.5 mg 3 times daily. Severe infections 1 caplet 625 mg 3 times daily. Tooth infections 1 caplet 312.5 mg 3 times daily for 5 days. Childn Usual dose: 30 mg/kg/day in divided doses 8 hrly.

Administration

May be taken with or without food.

Contraindications

Hypersensitivity to penicillins. Newborn babies born from mother w/ hypersensitivity to penicillin or its derivatives. History of cholestatic jaundice.

Special Precautions

High dose or prolonged use may cause superinfections. Severe liver disorders. Adjust dose in patients w/ moderate or severe kidney dysfunction.

Adverse Reactions

Diarrhea, nausea, vomiting, indigestion, pseudomembranous colitis & candidiasis. Slight increase in AST &/or ALT. Hepatitis & cholestatic jaundice. Urticaria & erythematous rashes. Erythema multiforme, SJS, TEN, exfoliative dermatitis. Angioedema & anaphylaxis. Interstitial nephritis. Transient leucopenia, thrombocytopenia, hemolytic anemia.

View ADR Monitoring Form

Drug Interactions

May reduce efficacy of OC. May increase bleeding time & prothrombin time in patients receiving anticoagulants.

MIMS Class

Penicillins

ATC Classification

J01CR02 - amoxicillin and beta-lactamase inhibitor ; Belongs to the class of penicillin combinations, including beta-lactamase inhibitors. Used in the systemic treatment of infections.

Regulatory Classification

Presentation/Packing

Form

Coyarin FC caplet

Packing/Price

5 × 6's

Coyarin

amoxicillin + clavulanic acid

Manufacturer:

Yarindo Farmatama