Concomitant use w/ sympathomimetic drugs including decongestants, TCAs, appetite suppressants & amphetamine-like psychostimulants, or w/ MAOIs may increase BP. Drugs that interfere w/ sympathetic activity including bretylium, bethanidine, guanethidine, debrisoquine, methyldopa, β & α adrenergic blockers. Alcohol or other sedatives acting on the CNS.