Treatment of infections caused by susceptible bacteria in lower resp tract including pneumonia & bronchopneumonia, lower UTI including pyelonephritis, skin & skin structure infections, severe or complicated gynecology infection, septicaemia, intra-abdominal infections including peritonitis & biliary tract infection. Empiric treatment of febrile neutropenia. Severe pneumonia in childn 2 mth-16 yr. Monotherapy prior to identification of causative organism in patients who are at risk of mixed aerobic-anaerobic infection caused by Bacteroides fragilis.
Dosage/Direction for Use
AdultMild to moderate UTI 500 mg-1 g IV/IM every 12 hr. Mild to moderate infections other than UTI 1 g IV/IM every 12 hr. Severe infections 2 g IV every 12 hr. Very severe or life-threatening infections 2 g IV every 8 hr. Childn 2 mth-16 yr Do not exceed adult dose. Childn up to 40 kgPneumonia 50 mg/kg/dose every 12 hr. Empiric therapy for febrile neutropenic patient 50 mg/kg/dose every 8 hr for 7-10 days. All IV administration is given approx 30 min.
Contraindications
Hypersensitivity to cefepime, cephalosporins, penicillins or other β-lactams.
Special Precautions
Discontinue use when allergic reactions occur. Renal impairment, pseudomembranous colitis. Pregnancy & lactation.
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