Rarely, diarrhea, pruritus, increase of liver enzyme, gallstone calcification, skin rashes, urticaria, dry skin, cold sweat, hair loss; nausea, vomiting, indigestion, metallic taste, abdominal & biliary pain, cholecystitis, constipation, stomatitis, flatulence; dizziness, fatigue, anxiety, depression, sleep disorder, arthralgia.