Depval Dosage & Drug Information

Concise Prescribing Info Bahasa Concise Prescribing Info

Concise Prescribing Info

Contents

Valproic acid

Indications/Uses

Monotherapy or adjunctive therapy to partial epilepsy (simple & complex) & absence seizure (petit mal).

Dosage/Direction for Use

Initially 15 mg/kg daily, increasing at 1-wk interval by 5-10 mg/kg daily until seizures are controlled & no aggravation of side effects. Max: 60 mg/kg daily. Dose >250 mg should be given in divided doses.

Administration

Should be taken with food.

Contraindications

Hypersensitivity. Patients w/ significant hepatic disease or dysfunction, urea cycle disorder.

Special Precautions

Liver dysfunction. Pregnancy & lactation. Childn.

Adverse Reactions

Nausea, vomiting, GI disorder, diarrhea, stomach cramps, constipation, anorexia, lose body wt, increased appetite & body wt; sedation, tremor, ataxia, headache, nystagmus, diplopia, asterixis, dysarthria, dizziness, incoordination; hair loss.

View ADR Monitoring Form

Drug Interactions

Alcohol, barbiturate, primidone, phenytoin, clonazepam, other anticonvulsants, coagulant/anticoagulant agents eg, aspirin & warfarin.

MIMS Class

Anticonvulsants

ATC Classification

N03AG01 - valproic acid ; Belongs to the class of fatty acid derivatives antiepileptic.

Presentation/Packing

Form

Depval syr 250 mg/5 mL

Packing/Price

120 mL x 1's (Rp72,600/botol)

Depval

valproic acid

Manufacturer:

Mersifarma TM