Dermovate

Dermovate

clobetasol

Manufacturer:

GlaxoSmithKline Indonesia
Concise Prescribing Info
Contents
Clobetasol propionate
Indications/Uses
Short-course treatment of resistant dermatoses eg, psoriasis (excluding widespread plaque psoriasis), recalcitrant eczema, lichen planus, discoid lupus erythematosus & other conditions which do not respond satisfactorily to less active steroids.
Dosage/Direction for Use
Adults, elderly & childn >1 yr Apply sparingly to the affected area once or twice times daily until improvement occurs & discontinue when control is achieved. Do not continue treatment for >4 wk w/o reviewing patient's condition.
Contraindications
Untreated cutaneous infections, rosacea, acne vulgaris, pruritus w/o inflammation, perianal & genital pruritus, perioral dermatitis. Dermatoses in childn <1 yr including dermatitis.
Special Precautions
History of local hypersensitivity to corticosteroids. W/draw gradually or substitute a less potent corticosteroid in case of manifestations of hypercortisolism (Cushing's syndrome) & reversible hypothalamic-pituitary-adrenal (HPA) axis suppression. Increased risk of systemic effects. Visual disturbances. Infection risk w/ occlusion. Caution in psoriasis as rebound relapses, development of tolerances, risk of generalized pustular psoriasis & development of local or systemic toxicity due to impaired barrier function of the skin. Concomitant infection. Treatment should be limited to 5 days if used on the face. Avoid contact w/ eyes. Contains paraffin; avoid smoking or go near naked flames. Pregnancy & lactation. Avoid long-term continuous therapy in infants & childn <12 yr.
Adverse Reactions
Pruritus, local skin burning/skin pain.
Drug Interactions
Increased systemic exposure w/ CYP3A4 inhibitors (eg, ritonavir, itraconazole).
MIMS Class
Topical Corticosteroids
ATC Classification
D07AD01 - clobetasol ; Belongs to the class of very potent (group IV) corticosteroids. Used in the treatment of dermatological diseases.
Presentation/Packing
Form
Dermovate cream 0.05%
Packing/Price
10 g x 1's;5 g x 1's
Form
Dermovate oint 0.05%
Packing/Price
10 g x 1's
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