One vial of powder for concentrate for solution for infusion contains 20 mg enfortumab vedotin.
After reconstitution, each mL of solution contains 10 mg of enfortumab vedotin.
Enfortumab vedotin is comprised of a fully human IgG1 kappa antibody, conjugated to the microtubule-disrupting agent monomethyl auristatin E (MMAE) via a protease-cleavable maleimidocaproyl valine-citrulline linker.
Excipients/Inactive Ingredients: Histidine, Histidine hydrochloride monohydrate, Trehalose dihydrate, Polysorbate 20.