Hypoglycemia, abdominal pain, nausea, vomiting, dyspepsia, diarrhea, constipation. Rash, pruritus, urticaria, angioedema, erythema, maculopapular rashes, bullous reactions eg, SJS & TEN & autoimmune bullous disorders, & exceptionally, DRESS. Changes in haematology generally reversible (anaemia, leucopenia, thrombocytopenia, granulocytopenia). Raised hepatic enzymes levels (AST, ALT, alkaline phosphatase), hepatitis (isolated reports). If cholestatic jaundice: discontinuation of treatment. Transient visual disturbances at start of treatment. As for other sulfonylureas: observed cases of erythrocytopenia, agranulocytosis, haemolytic anaemia, pancytopenia, allergic vasculitis, hyponatraemia, elevated liver enzymes, impairment of liver function (cholestasis, jaundice) & hepatitis which led to life-threatening liver failure in isolated cases.
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