Diethylamine salicylate: Indication, Dosage, Side Effect, Precaution

Generic Medicine Info Patient Medicine Information

This information is not country-specific. Please refer to the Indonesia prescribing information.

Generic Medicine Info

Indications and Dosage

Topical/Cutaneous
Musculoskeletal pain

Adult: As 10% w/w cream: Apply onto the affected area 2 or 3 times daily. Use sparingly.
Child: ≥6 years Same as adult dose.

Contraindications

Hypersensitivity to diethylamine salicylate, aspirin, or other NSAIDs (including oral hypersensitivity) particularly when associated with history of asthma. Application on broken, abraded, or cut skin.

Special Precautions

Patient with asthma. Children. Pregnancy and lactation.

Adverse Reactions

Skin and subcutaneous tissue disorders: Temporary skin reactions (e.g. rashes, redness, discomfort, irritation, burning sensation).

Patient Counseling Information

Avoid contact with eyes and sensitive skin areas.

Drug Interactions

May enhance the anticoagulant effects of warfarin. May increase the blood concentrations and risk of toxicity of methotrexate.

Action

Description:
Mechanism of Action: Diethylamine salicylate is a salicylic acid derivative topical analgesic. It has the anti-inflammatory effects of salicylates and may be used as a counterirritant.
Pharmacokinetics:
Absorption: Absorbed through the skin (small amounts as salicylic acid).
Excretion: Via urine.

Chemical Structure

Storage

Store below 25°C.

MIMS Class

Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

References

Algesal Cream (Thornton & Ross Limited). MHRA. https://products.mhra.gov.uk/. Accessed 02/10/2020.

Anon. Diethylamine Salicylate. Lexicomp Online. Hudson, Ohio. Wolters Kluwer Clinical Drug Information, Inc. https://online.lexi.com. Accessed 02/10/2020.

Buckingham R (ed). Diethylamine Salicylate. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 02/10/2020.

Odour Free Lloyds Cream (Thornton & Ross Limited). MHRA. https://products.mhra.gov.uk/. Accessed 02/10/2020.

Disclaimer: This information is independently developed by MIMS based on Diethylamine salicylate from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2024 MIMS. All rights reserved. Powered by MIMS.com