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Indications and Dosage
Ophthalmic
Ocular hypertension, Open-angle glaucoma Adult: As hydrochloride: Instil 1 drop of 0.1% soln in the eye/s every 12 hr.
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Contraindications
Hypersensitivity. Patients with narrow angles, since any pupillary dilatation may cause an attack of angle-closure glaucoma.
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Special Precautions
Aphakic patients; lactation.
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Adverse Reactions
Ocular hyperaemia, burning, stinging, irritation, follicular conjunctivitis, mydriasis, allergic reactions, adrenochrome deposits in the conjunctiva and cornea, headache, browache and eye pain. Very rarely, tachycardia and hypertension may occur.
Potentially Fatal: Generally well tolerated. Side effects fewer when compared to epinephrine drops. |
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Ophth: B
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Drug Interactions
Additive ocular hypotensive effects with other anti-glaucoma drugs.
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Action
Description:
Mechanism of Action: Dipivefrine is a prodrug of adrenaline. It reduces IOP by decreasing aqueous production and by enhancing outflow. |
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MIMS Class
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