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Indications and Dosage
Oral
Reversible airways obstruction Adult: 15 mg/kg every 6 hr.
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Renal Impairment
Use with caution.
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Administration
Should be taken on an empty stomach. Take 1 hr before or 1 hr after meals.
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Contraindications
Hypersensitivity.
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Special Precautions
Peptic ulceration, hyperthyroidism, hypertension, cardiac arrhythmias or other CV diseases, epilepsy, hepatic dysfunction, chronic alcoholism, acute febrile illness; smoking; neonates; elderly; pregnancy, lactation; impaired renal function.
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Adverse Reactions
GI irritation and disturbances, CNS stimulation, headache, anxiety, restlessness, dizziness, tremor, palpitations.
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Drug Interactions
Probenecid; xanthines (additive effects).
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Action
Description:
Mechanism of Action: Diprophylline is a theophylline derivative which is used similarly to theophylline as a bronchodilator. Pharmacokinetics: Absorption: Rapidly absorbed from the GI tract. Distribution: Distributed into breast milk. Excretion: Mainly excreted unchanged in the urine. Elimination half-life: About 2 hr. |
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MIMS Class
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