Adult & adolescent ≥16 yr Initially 2 caplet. Max: 8 caplet/day. Min dosing interval should not be <6 hr.
Administration
May be taken with or without food: Swallow whole, do not break/chew.
Contraindications
Hypersensitivity. Acute intoxication w/ alcohol, hypnotics, centrally-acting analgesics, opioids or psychotropic drugs. Patients receiving MAOIs or w/in 2 wk of w/drawal. Severe hepatic impairment. Epilepsy not controlled by treatment. Pregnancy & lactation.
Special Precautions
Renal & hepatic insufficiency, non-cirrhotic alcoholic liver disease; severe resp insufficiency. Not suitable in opioid dependent patient. Patients susceptible to seizure or taking other drugs that lower seizure threshold. Cranial trauma, biliary tract disorders, state of shock, altered state of consciousness for unknown reasons, increased intracranial pressure. May impair ability to drive or operate machinery. Childn <16 yr.
Sign Out
