Emflozin Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Empagliflozin

Indications/Uses

Monotherapy when metformin is considered inappropriate due to intolerance or in addition to other medicinal products as adjunct to diet & exercise in adults w/ insufficiently controlled type 2 DM.

Click to view Emflozin detailed prescribing information

Dosage/Direction for Use

Monotherapy & add-on combination therapy Initially 10 mg once daily, may be increased to 25 mg once daily if additional glycaemic control is needed. Max daily dose: 25 mg.

Click to view Emflozin detailed prescribing information

Overdosage

View Emflozin overdosage for action to be taken in the event of an overdose.

Administration

May be taken with or without food: Swallow whole w/ water.

Contraindications

Hypersensitivity.

Click to view Emflozin detailed prescribing information

Special Precautions

Not to be used in patients w/ type 1 diabetes or for diabetic ketoacidosis. Increased haematocrit. Complicated UTIs. Patients w/ known CV disease, on antihypertensive therapy w/ history of hypotension or ≥75 yr. Increased risk of vol-depletion in patient ≥75 yr. Assess renal function prior to & periodically during treatment. Monitor vol status & electrolytes. Counsel patients on routine preventive foot care. +ve test for glucose in urine. Not be initiated in patients w/ eGFR <60 mL/min/1.73 m² or CrCl <60 mL/min; ESRD or on dialysis. Not recommended in severe hepatic impairment. Hepatic injury. Avoid during pregnancy. Not to be used during lactation. Childn & adolescents. Not recommended in elderly ≥85 yr.

Click to view Emflozin detailed prescribing information

Use In Pregnancy & Lactation

Click to view Emflozin detailed prescribing information

Adverse Reactions

Hypotension; ketoacidosis; acute kidney injury & renal impairment; urosepsis & pyelonephritis; hypoglycemia; genital mycotic infections; increased LDL-C.

Click to view Emflozin detailed prescribing information

Drug Interactions

May add to the effect of thiazide & loop diuretics & may increase risk of dehydration & hypotension. May increase risk of hypoglycaemia w/ insulin & insulin secretagogues eg, sulphonylureas. Potential risk of decreased efficacy w/ UGT inducers.

Click to view Emflozin detailed prescribing information

Storage

View Emflozin storage conditions for details to ensure optimal shelf-life.

Description

View Emflozin description for details of the chemical structure and excipients (inactive components).

Action

View Emflozin mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Antidiabetic Agents

ATC Classification

A10BK03 - empagliflozin ; Belongs to the class of sodium-glucose co-transporter 2 (SGLT2) inhibitors. Used in the treatment of diabetes.

Regulatory Classification

POM

Presentation/Packing

Form

Emflozin FC tab 10 mg

Packing/Price

3 × 10's

Form

Emflozin FC tab 25 mg

Packing/Price

3 × 10's

Emflozin

empagliflozin

Manufacturer:

Zifam Pinnacle

Distributor:

Pinnacle House