IV inj or infusion Adult Gastric antisecretory 20-40 mg once daily.
Reflux oesophagitis 40 mg once daily.
Symptomatic treatment of reflux disease; healing of gastric ulcers associated w/ NSAID therapy 20 mg once daily.
Maintenance of haemostasis & prevention of gastric & duodenal ulcer rebleeding Following therapeutic endoscopy for acute bleeding gastric or duodenal ulcers, 80 mg as bolus infusion over 30 min, followed by continuous IV infusion of 8 mg/hr for 3 days (72 hr). The parenteral treatment period should be followed by acid-suppression therapy w/ esomeprazole 40 mg tab once daily for 4 wk.
Severe hepatic impairment: GERD Max: 20 mg daily;
bleeding ulcers Initially 80 mg as bolus infusion, followed by 4 mg/hr continuous IV infusion for 71.5 hr.