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Indications and Dosage
Extra-amniotic
Medical termination of pregnancy after first trimester Adult: 10 ml/gestational wk of 0.1% solution (max: 200 ml), to be slowly instilled extra-amniotically using a Foley catheter. Catheter is then clamped at its lower end and left in place for 24 hr unless expelled earlier.
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Contraindications
Hypersensitivity, pregnancy.
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Adverse Reactions
Hypersensitivity, prolonged use delays wound healing.
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Drug Interactions
Activity enhanced by alkaline solutions.
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Action
Description:
Mechanism of Action: Induces abortion after extra-amniotic instillation. |
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