Contraindications
Respiratory depression, obstructive airway disease, asthma. Acute alcoholism, convulsive disorders, head injuries, comatose patients, raised intracranial pressure.
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Special Precautions
Hypothyroidism, adrenocortical insufficiency; asthma, impaired hepatic or renal function, prostatic hyperplasia, hypotension, shock, inflammatory or obstructive bowel disorders, myasthenia gravis. Infants, neonates; Reduce dose in elderly or debilitated patients. May impair ability to drive or operate machinery. Pregnancy and lactation.
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Adverse Reactions
Dependence, withdrawal symptoms; nausea, vomiting, constipation; drowsiness, confusion; difficulty in micturition, ureteric or biliary spasms, urinary retention; dry mouth, dizziness, sweating, facial flushing, headache, vertigo, bradycardia, tachycardia, palpitations, orthostatic hypotension, hypothermia, restlessness, mood changes, decreased libido or potency, hallucination, miosis; raised intracranial pressure, muscle rigidity.
Potentially Fatal: Respiratory depression and hypotension, with circulatory failure and deepening coma (larger doses). Convulsions (especially in childn and infants). Rhabdomyolysis. |
Drug Interactions
Enhanced depressant effects with alcohol, anaesthetics, anxiolytics, hypnotics, tricyclic antidepressants, antipsychotics. Possible CNS depression or excitation with MAOIs. May alter effects of other compounds eg, cyclizine, mexiletine, cisapride, metoclopramide and domperidone.
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Action
Description:
Mechanism of Action: Ethylmorphine HCl has actions similar to that of codeine and is used as a cough suppressant. |
MIMS Class
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