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Indications and Dosage
Oral
Hyperlipidaemias Adult: 500 mg daily.
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Administration
Should be taken with food. Best taken after the evening meal.
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Contraindications
Liver diseases; gallbladder diseases; severe renal insufficiency; decompensated heart failure; acute cardiac infarct; acute bleedings; pregnancy; lactation.
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Special Precautions
Perform regular liver function tests. May increase the risk of cholelithiasis. Regular monitoring of INR when used with coumarin-type anticoagulants.
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Adverse Reactions
Flush syndrome and reactions to flush; GI disorders.
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Drug Interactions
Anticoagulants; sulfonylureas; HMG-CoA reductase inhibitors; coronary vasodilating drugs. Increased risk of nephrotoxicity with cyclosporine.
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Action
Description:
Mechanism of Action: Etofibrate, a clofibrate and nicotinic acid derivative, is a lipid-regulating drug. |
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MIMS Class
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