Early treatment: 3 bolus IV inj of 5 mg given approx at 2-min interval. Shifting to oral therapy:
Patients who tolerate full IV dose 50 mg metoprolol tartrate tab 6 hrly, initiated at 15 min after the last IV dose & continued for 48 hr.
Patients who do not tolerate full IV dose 25 or 50 mg metoprolol tartrate tab 6 hrly, initiated at 15 min after the last IV dose as soon as clinical condition allows. Late treatment:
Patients w/ contraindications to early phase treatment, cannot tolerate full early treatment or in whom physician wishes to delay therapy 100 mg metoprolol tartrate tab twice daily as soon as clinical condition allows & continued for at least 3 mth.