Avoid contact w/ the eyes. Patients predisposed to glaucoma, insufficiently controlled DM, recent MI, severe organic heart or vascular disorders, hyperthyroidism, phaeochromocytoma, risk of narrow-angle glaucoma, prostatic hypertrophy or bladder-neck obstruction, hypoxia, cystic fibrosis. Avoid prolonged use. Pregnancy & lactation. Childn <12 yr.