Edema due to heart failure, liver cirrhosis, kidney disease including nephrotic syndrome. Mild to moderate HTN, as mono or combination therapy.
Dosage/Direction for Use
EdemaAdult Initially 20-80 mg as a single dose, if necessary, doses may be repeated 6-8 hr later. Doses may be increased by 20-40 mg 6-8 hrly until the expected diuretic effect is achieved. Then doses is given 1-2 times daily. Patients w/ severe edema: Doses may be increased to 600 mg daily. Childn Initially 1-2 mg/kg as a single dose. If the expected response is not achieved, doses may be increased by 1-2 mg/kg 6-8 hrly until the expected diuretic is achieved. Max dose: 6 mg/kg. For maintenance, reduce dose until the effective minimal dose. HTN 40 mg twice daily.
Administration
Should be taken on an empty stomach: If GI distress occurs, take w/ food or milk.
Contraindications
Hypersensitivity to furosemide or sulfonamide. Anuria.
Special Precautions
Patients w/ electrolyte deficiency. Lab exam should be performed in prolonged use & large dose. Discontinue therapy if increased azotemia & oliguria occur in the treatment of severe kidney disease. In overdose, dehydration or electrolyte deficiencies may occur especially in elderly. Pregnancy, lactation.
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