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Indications and Dosage
Oral
Antispasmodic Adult: 100 mg tid or 200 mg bid for not >6 wk.
Elderly: Max: 100 mg tid. |
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Administration
Should be taken with food.
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Contraindications
Hypersensitivity, chronic liver disease, history of hyperthermia during or after anaesthesia or after physical effort, renal insufficiency, mitochondrial myopathy, pregnancy, lactation.
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Special Precautions
In patients with renal or hepatic insufficiency and in patients >60 yr or with multiple drug therapy, in case of unexplained muscular pain or if myopathy is diagnosed.
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Adverse Reactions
Myalgias, reversible rhabdomyolysis, gastric upset.
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Action
Description:
Mechanism of Action: Fenoverine is a non-anticholinergic synchronizer of smooth muscle motility. It modulates calcium gradient across the muscular cell membrane by regulating the influx of the extracellular calcium and/or release of the intracellular pool. Therefore, fenoverine effectively inhibits the asynchronous spasmodic contractions without appreciable interferences with the physiological synchronous motility of the intestine. Pharmacokinetics: Absorption: Oral: Well absorbed. |
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Storage
Store below 25°C.
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MIMS Class
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