Adult 2-4 g in 2 divided doses 12 hrly, may be increased up to 8 g daily in severe or refractory infections. Childn 40-80 mg/kg/day in divided doses 6-12 hrly, may be increased up to 160 mg/kg/day in severe or refractory infections.
Contraindications
Hypersensitivity to penicillin or cephalosporin.
Special Precautions
Hepatic dysfunction & concomitant renal impairment; overgrowth of nonsusceptible organisms.
Adverse Reactions
Diarrhea, nausea, vomiting, maculopapular rash, urticaria, eosinophilia, drug fever.
J01DD62 - cefoperazone and beta-lactamase inhibitor ; Belongs to the class of third-generation cephalosporins. Used in the systemic treatment of infections.