Cryptococcocal meningitis Day-1: 400 mg as a single dose, Day-2 onwards: 200-400 mg daily. Systemic candidiasis Day-1: 400 mg as a single dose, then 200 mg daily. Dose may be increased to 400 mg daily. Oropharyngeal candidiasis 50 mg once daily for 1-2 wk. If necessary, can be continued for maintenance. Max dose: 100 mg. Vag candidiasis 150 mg as a single oral dose.
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