Hypersensitivity. Periodic lab tests should be performed for long-term use. Elderly w/ high fever or patients w/ wasting disease. Do not co-administer w/ enoxacin hydrate, lomefloxacin, norfloxacin or prulifloxacin. Avoid use w/ other new quinolone antibiotics. Interruption or discontinuation of the drug if cutaneous symptoms are observed. Patients w/ peptic ulcer-induced by long-term use of NSAID who need long term use of esflurbiprofen & those being treated w/ agents eg, misoprostol, history of peptic ulcer, current or previous blood abnormality, bleeding tendency, current or previous liver/renal disorder or reduced renal blood flow, abnormal cardiac function, HTN, bronchial asthma, ulcerative colitis, Crohn's disease. Temporary infertility in women (long-term use). Pregnancy. Avoid during lactation. Low birth wt babies, neonates, nursing infants & childn.
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