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Neurology
Mild neurocognitive disorders (NCDs) are present in one in five community-dwelling older adults in Hong Kong, while 70 percent of older adults living in residential care homes have dementia, researchers from the Chinese University of Hong Kong (CUHK) have reported.
An intranasally administered recombinant human erythropoietin without erythropoietic activity and shorter plasma half-life (neuroEPO) restores cognitive function or delays progression in most patients with mild-to-moderate Alzheimer’s disease, results of the phase II/III double-blind, placebo-controlled ATHENEA trial have shown.
Apathy may have a significant impact on cognitive health of stroke survivors, according to results of a cross-sectional study by the Chinese University of Hong Kong.
Spinal muscular atrophy (SMA) is a genetic disorder characterized by progressive muscle weakness and atrophy, leading to impaired motor function. Until recently, management of SMA was primarily supportive, but new treatments have improved disease prognosis. At an industry-sponsored symposium organized by the Hong Kong Neurological Society, Professor Maggie Walter of the Ludwig Maximilians University of Munich, Munich, Germany, discussed the importance of early detection of SMA and timely administration of disease-modifying therapies, such as the oral drug risdiplam (Evyrsdi®), to prevent rapid and irreversible loss of motor function in adult patients. Dr Shirley Pang of the Division of Neurology, Queen Mary Hospital, Hong Kong, shared local experience with the use of risdiplam in adults with SMA.
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Upfront perfusion imaging may extend time window for endovascular thrombectomy (EVT) beyond 24 hours in patients with acute ischaemic stroke due to large vessel occlusion (LVO-AIS), according to data presented at AIM 2023.
