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Dupilumab benefits in kids with asthma hold out to 52 weeks

A healthy heart prevents adult-onset asthma: study

20240116110000

Maintaining good cardiovascular health (CVH) can help avert incident adult-onset asthma (AOA) regardless of a person’s asthma genetic risks, according to a study.

Inhaled amikacin cuts VAP burden in mechanically ventilated patients

Audrey Abella, 20240116100000

In critically ill patients who have been on invasive mechanical ventilation (IMV) for at least 3 days, a subsequent 3-day course of preventive inhaled amikacin reduced the burden of ventilator-associated pneumonia (VAP) during 28 days of follow-up, findings from the AMIKINHAL trial have shown.

Dietary nitrate boosts exercise capacity in COPD

20240115180000

Dietary nitrate supplementation for patients with chronic obstructive pulmonary disease (COPD) appears to lead to better exercise capacity, according to a study.

Add-on clarithromycin boosts recovery from pneumonia

20240113060000

Adding clarithromycin to standard of care appears to improve clinical response and reduce inflammation in patients with community-acquired pneumonia, as reported in the phase III ACCESS trial.

Tiotropium beneficial to patients with mild COPD

20240112180000

Treatment with tiotropium appears to reduce the risk of clinically important deterioration (CID) in patients with mild-to-moderate chronic obstructive pulmonary disease (COPD), including those with fewer respiratory symptoms, according to a study.

Adjuvant alectinib benefits Asians with resected ALK+ NSCLC

Elvira Manzano, 20240109000000

Adjuvant treatment with alectinib, an anaplastic lymphoma kinase (ALK) inhibitor, significantly improved disease-free survival (DFS) better than platinum-based chemotherapy at 2 years in Asian patients with early-stage, completely resected ALK-positive non–small cell lung cancer (ALK+ NSCLC) in an exploratory analysis of the phase III ALINA trial.

mRNA boosters protect cancer patients against adverse COVID-19 outcomes

Audrey Abella, 20240108100000

A prospective study from Singapore provides evidence of the clinical effectiveness of mRNA-based vaccines against COVID-19 in individuals with cancer.

Singapore faces high asthma burden

Jairia Dela Cruz, 20240105140000

Singapore is disproportionately burdened by asthma, with related hospitalizations and emergency department (ED) visits occurring twice as often as the average of other developed countries, according to a study.

Fluvoxamine of little benefit in mild-to-moderate COVID-19

20240102060000

The use of fluvoxamine for outpatient treatment of mild-to-moderate COVID-19 falls short of reducing the duration of symptoms, as shown in the ACTIV-6 study.

Severe outcomes more likely with Omicron XBB.1.16 in SG

Audrey Abella, 20231229100000

In a preliminary analysis, the risk of severe outcomes was higher in individuals infected with the Omicron XBB.1.16 subvariant compared with those who were infected with other subvariants such as the XBB.1.5 or XBB.1.9.