Adult & elderly Severe erosive or ulcerative GERD 20 mg once daily for 4-8 wk. Maintenance: 10-20 mg daily depending on response.
Symptomatic disease w/ or w/o erosive or ulcerative oesophagitis 10-20 mg once daily for 4 wk.
Active PUD 20 mg daily, 4-8 wk for duodenal ulcer & 6-12 wk for gastric ulcer.
Eradication of H. pylori 20 mg bid + clarithromycin 250 mg bid + metronidazole 400 mg bid for 1 wk.
Zollinger-Ellison syndrome 60 mg once daily or up to 100-120 mg daily in 2 divided doses.