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Tezspire

Tezspire

Manufacturer:

AstraZeneca

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Tezepelumab
Indications/Uses
Add-on maintenance treatment for inadequately controlled severe asthma despite medium or high dose inhaled corticosteroids plus another medicinal product for maintenance treatment, in adult & adolescent ≥12 yr.
Dosage/Direction for Use
SC Adult & adolescent ≥12 yr 210 mg every 4 wk.
Contraindications
Special Precautions
Hypersensitivity reactions (eg, anaphylaxis, rash) may occur following administration. Not to be used to treat acute asthma exacerbations. Advise patients to seek medical advice if their asthma remains uncontrolled or worsens after treatment initiation. Abrupt corticosteroid discontinuation after initiation of Tezspire therapy is not recommended; reduce dose gradually, if appropriate. Known helminth infection; discontinue use if the patient becomes infected while receiving Tezspire treatment & does not respond to anti-helminth treatment. Serious cardiac adverse events may occur; discontinue use until acute event stabilises, if the patient develops a serious cardiac event during treatment. Treat preexisting serious infections prior to Tezpire treatment initiation. Not recommended to be used during pregnancy. Lactation; consider the benefit & risk of breast-feeding for the child & the benefit of therapy for the woman.
Adverse Reactions
Pharyngitis; rash; arthralgia; inj site reaction.
Drug Interactions
Avoid use of live attenuated vaccines.
MIMS Class
Other Drugs Acting on the Respiratory System
ATC Classification
R03DX11 - tezepelumab ; Belongs to the class of other systemic drugs used in the treatment of obstructive airway diseases.
Presentation/Packing
Form
Tezspire soln for inj 210 mg/1.91 mL
Packing/Price
1's
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